February 6, 2023

Taylor Daily Press

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Discovery of new bacterial species in enteritis

Researchers from UMC Utrecht and Yale University have identified two new types of bacteria in patients with inflammatory bowel disease (IBD). explore. These new species break down the protective mucosa of the intestinal wall, causing violent immune reactions.

Using Culturomics, the researchers were able to isolate two types of new bacteria from the intestines of patients with IBD: mucilyticum allobicum And Lopacula Philly.

Although the findings are still preliminary, the researchers said, it is tempting to speculate that new bacterial species play a role in the development of intestinal infections such as those seen in patients with IBD.

After extensive DNA analysis, it turned out that the new species are distant cousins Erysipelothrix rhusiopathiaeIt is a pathogenic bacterium that infects different animal species such as pigs, turkeys, and chickens, but also occasionally infects humans.

In two additional studies, the researchers then looked at properties mucilyticum allobicum. It turned out to be a very effective substance for destroying the intestinal mucosa. It has also been demonstrated with researchers from Yale University mucilyticum allobicum It caused intestinal inflammation in infected mice and disrupted the immune response to commensal human bacteria.


UMC Utrecht

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